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AM: After cleansing, close your eyes and spritz all over the face, neck, and v-area. Gently massage into skin leaving it slightly moist. Immediately apply the next Bioelements product and end with a broad-spectrum sunscreen.PM: After cleansing, close your eyes and spritz all over your face, neck, and v-area. Gently massage into skin leaving it slightly moist. Immediately apply the next Bioelements nighttime formula in your routine.Use twice daily or as needed throughout the day.